Direct metabolic effects of gastric inhibitory polypeptide (GIP): dissociation at physiological levels of effects on insulin-stimulated fatty acid and glucose incorporation in rat adipose tissue

Effects of glycogen stores and non-ester

Effects of glycogen stores and non-esterified fatty acid availability on insulin-stimulated glucose metabolism and tissue pyruvate dehydrogenase activity in the rat

✍ Y. T. Kruszynska; J. G. McCormack; N. McIntyre 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 820 KB

The effects of increased tissue glycogen stores on insulin sensitivity, and on the response of insulin-stimulated glucose utilisation to an acute elevation in plasma fatty acid levels (-1.5 mmol/1), were investigated in conscious rats using the hyperinsulinaemic euglycaemic clamp. Studies were perfo