𝔖 Bobbio Scriptorium
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Direct Lithiation of glycals. Synthesis of C-2 branched sugars

✍ Scribed by Richard R. Schmidt; Jürgen Kast

Book ID
104218976
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
244 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis

Direct Zithiation at the C-2 atom of l-phenylsuZfiny7, substituted glucals c??b_ can be readiZy performed with LDA as indicated by reactions with different C-eZectrophZe5. Phenyikulfinyi: group remova takes place in the aldehyde reaction products by simple thermal treatment affording directly 2-aZkyZidene substituted gZuconoZactones.

📜 SIMILAR VOLUMES

Diastereoselective synthesis of branched
Diastereoselective synthesis of branched 2-deoxy sugars via radical c-c bond formation reactions
✍ Bernd Giese; Kay Gröninger 📂 Article 📅 1984 🏛 Elsevier Science 🌐 French ⚖ 201 KB

From glycals l and 5, 2-deoxy sugars can be synthesized in 40-728 yields. With 1,2\_disubstituted alkenes 1 this radical C-C bond formation reaction leads with high stereoselectivity to the isomers The formation of C-C bonds via solvomercuration of electron-rich alkenes and reduction with hydrides i