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Direct inhibitions of the activities of steroidogenic cytochrome P-450 mono-oxygenase systems by anticonvulsants

✍ Scribed by Ohnishi, Taira; Ichikawa, Yoshiyuki

Book ID
122928148
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
906 KB
Volume
60
Category
Article
ISSN
0960-0760

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## Abstract Copper toxicity has been associated to the capacity of free copper ions to catalyze the production of superoxide anion and hydroxyl radical, reactive species that modify the structure and/or function of biomolecules. In addition, nonspecific Cu^2+^‐binding to thiol enzymes, which modifi