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Direct inhibition of smooth muscle myosin light chain kinase by arachidonic acid in a purified system

✍ Scribed by Toshikazu Kigoshi; Kenzo Uchida; Mihoko Kaneko; Ryoji Iwasaki; Shigeru Nakano; Sadahide Azukizawa; Shinpei Morimoto


Book ID
115763306
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
604 KB
Volume
171
Category
Article
ISSN
0006-291X

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Effects of a myosin light chain kinase i
✍ Makoto Takayama; Hiroshi Ozaki; Hideaki Karaki πŸ“‚ Article πŸ“… 1996 πŸ› Springer-Verlag 🌐 English βš– 870 KB

Biochemical studies have shown that wortmannin is an inhibitor of myosin light chain (MLC) kinase (Nakanishi et al. (1992) J. Biol. Chem. 267: 2157-2163). To investigate the role of MLC kinase in smooth muscle contractions, we examined the effects of wortmannin on isolated smooth muscles of the rat