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Direct High-Performance Liquid Chromatographic Separation of Peptide Enantiomers: Study on Chiral Recognition by Systematic Evaluation of the Influence of Structural Features of the Chiral Selectors on Enantioselectivity

✍ Scribed by Czerwenka, Christoph; Lämmerhofer, Michael; Maier, Norbert M.; Rissanen, Kari; Lindner, Wolfgang


Book ID
118221798
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
188 KB
Volume
74
Category
Article
ISSN
0003-2700

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Structure-enantioselectivity relationshi
✍ Christoph Czerwenka; Michael Lämmerhofer; Wolfgang Lindner 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 314 KB

## Abstract Eleven different N‐terminal protecting groups (acetyl, benzoyl, FMOC, etc.) were employed for the HPLC separation of oligoalanine peptide enantiomers containing up to six amino acids. Isocratic HPLC separations were performed using a hydro‐organic buffered mobile phase and 4 mm ID colum