Direct Generation of Polymer Films on Copper Surfaces through Azide-Alkyne Cycloaddition Reactions between Peptidomimetic Oligomers
✍ Scribed by Neel H. Shah; Kent Kirshenbaum
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 294 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1022-1336
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✦ Synopsis
Abstract
N‐substituted glycine oligomers, or peptoids, can be used in conjunction with the copper‐catalyzed [3 + 2] cycloaddition of azides and alkynes to generate branched polymer networks. By incorporating both azides and alkynes as side chain functionalities on the oligomer scaffolds, peptoids are able to form cross‐linked macromolecular products. The oligomer starting materials are readily associated onto copper metal sheets, allowing for localized cross‐link proliferation which in turn generates thin film polymer coatings. This novel procedure provides a direct method for the chemical modification of metal surfaces and the formation of mechanically robust sequence‐specific polymer networks.
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