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Direct Fluorescence Polarization Assay for the Detection of Glycopeptide Antibiotics

✍ Scribed by Yu, Linliang; Zhong, Meng; Wei, Yinan


Book ID
111867697
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
245 KB
Volume
82
Category
Article
ISSN
0003-2700

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A fluorescent ligand for binding studies
✍ Paul H. Popieniek; R.F. Pratt πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 English βš– 542 KB

A fluorescent tripeptide, epsilon-N-acetyl-alpha-N-dansyl-L-lysyl-D-alanyl-D-alanine, has been prepared in order to study the thermodynamics and kinetics of the binding of peptides and peptide analogs to the glycopeptide antibiotics. On titration of the tripeptide with typical examples of these anti