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Direct evidence on the role of NKT cells in the control of T cell-mediated autoimmune diabetes in NOD mice

โœ Scribed by Yang Yang; Min Bao; Ji-Won Yoon

Book ID
117370117
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
147 KB
Volume
50
Category
Article
ISSN
0168-8227

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Contribution of T cells to the development of autoimmune diabetes in the NOD mouse model
โœ Hiroo Toyoda; Bent Formby ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 96 KB ๐Ÿ‘ 2 views

The nonobese diabetic (NOD) mouse spontaneously develops an autoimmune diabetes that shares many immunogenetic features with human insulin-dependent diabetes mellitus (IDDM), type 1 diabetes. The mononuclear cell infiltrates in the islet, which results in the development of insulitis (a prerequisite