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Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila

โœ Scribed by Haag-Liautard, Cathy; Dorris, Mark; Maside, Xulio; Macaskill, Steven; Halligan, Daniel L.; Charlesworth, Brian; Keightley, Peter D.


Book ID
109896362
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
158 KB
Volume
445
Category
Article
ISSN
0028-0836

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Direct estimates of human per nucleotide
โœ Alexey S. Kondrashov ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 235 KB

I estimate per nucleotide rates of spontaneous mutations of different kinds in humans directly from the data on per locus mutation rates and on sequences of de novo nonsense nucleotide substitutions, deletions, insertions, and complex events at eight loci causing autosomal dominant diseases and 12 l