Direct enantiomeric separations of tris(2-phenylpyridine) iridium (III) complexes on polysaccharide derivative-based chiral stationary phases

✍ Scribed by Xiaoming Chen; Yoshio Okamoto; Tomohiro Yano; Joe Otsuki

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 378 KB
• Volume: 30
• Category: Article
• ISSN: 1615-9306
• DOI: 10.1002/jssc.200600409

✦ Synopsis

Abstract

A convenient method is presented for the first time for the direct separation of enantiomers of a tris(2‐phenylpyridine) iridium (III) and an analog substituted with long alkoxy chains on polysaccharide derivative‐based chiral stationary phases by HPLC. Tris(2‐phenylpyridine) iridium (III) was separated on the immobilized amylose 3,5‐dimethylphenylcarbamate (Chiralpak IA) using hexane/CHCl~3~/CH~2~Cl~2~ (75:20:5) as an eluent, and the analog could be separated on the coated cellulose 3,5‐dimethylphenylcarbamate (Chiralcel OD) and cellulose 4‐methylbenzoate (Chiralcel OJ) using hexane/2‐propanol (96:4) as the eluent. CD spectra of the eluted HPLC fractions were also recorded, and the observed mirror image patterns confirm their enantioseparations.