Direct Electrochemistry of Cytochrome P450 Reductases in Surfactant and Polyion Films
✍ Scribed by Nasreen Sultana; John B. Schenkman; James F. Rusling
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 251 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1040-0397
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Aristolochic acid (AA), a naturally occurring nephrotoxin and carcinogen, has been associated with the development of urothelial cancer in humans. Understanding which human enzymes are involved in AA activation and/or detoxication is important in the assessment of an individual's suscep
The concept of relative activity factor (RAF) to extrapolate data obtained with recombinant cytochrome P450(CYP)s to human liver microsomes has been proposed. To evaluate the approach to predict the contribution of multiple CYPs using RAF, we investigated the effects of the differences in the expres