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Direct effects of nucleoside reverse transcriptase inhibitors on rat cardiac mitochondrial bioenergetics

✍ Scribed by Kaleb C. Lund; Kendall B. Wallace


Book ID
116751407
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
313 KB
Volume
4
Category
Article
ISSN
1567-7249

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A bacterial assay was developed for testing HTLV-1 reverse transcriptase sensitivity to common nucleoside analog inhibitors in an Escherichia coli strain characterized by a temperature sensitive PolI/RecA deletion phenotype. This genetic complementation assay exploits the ability of HTLV-1 reverse t