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Direct effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on responses to lipopolysaccharide (LPS) by isolated murine B-cells

โœ Scribed by Morris, Dale L. (author);Karras, James G. (author);Holsapple, Michael P. (author)


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
663 KB
Volume
26
Category
Article
ISSN
0162-3109

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## Abstract Wasting syndrome is one of the hallmark symptoms of poisoning by TCDD (=dioxin), which is associated with the massive loss of adipose tissue and serum hyperlipidemia in vivo. Yet, the most widely used in vitro cell model 3T3โ€L1 adipocyte has not been useful for studying such an action o