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Direct determination of haplotypes from single DNA molecules

โœ Scribed by Xiao, Ming; Wan, Eunice; Chu, Catherine; Hsueh, Wen-Chi; Cao, Yang; Kwok, Pui-Yan


Book ID
109935382
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
303 KB
Volume
6
Category
Article
ISSN
1552-4450

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Determination of haplotypes from single
โœ Ming Xiao; Matthew P. Gordon; Angie Phong; Connie Ha; Ting-Fung Chan; Dongmei Ca ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 339 KB ๐Ÿ‘ 1 views

## Communicated by Richard Cotton Determining the haplotypes in a diploid individual is a major technical challenge in genetic studies of human complex traits. Here we report a method of molecular haplotyping by directly imaging multiple polymorphic sites on individual DNA molecules simultaneously