Direct Determination of Barbiturates in Urine by Capillary Electrophoresis Using a Capillary Coated Dynamically with Polycationic Polymers
β Scribed by Ting-Fu Jiang; Yuan-Hong Wang; Zhi-Hua Lv; Mei-E Yue
- Book ID
- 111790736
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 362 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0009-5893
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CZE allows to measure the acidic dissociation constant (pKa) of many drug substances. However, determining the EOF intensity may be time-consuming, especially at a low pH. In order to overcome this drawback, a dynamic coating procedure of the capillary was carried out to increase microEOF, and thus
## Abstract Methods for separation and determination of multiple drugs of abuse in biological fluids using capillary electrophoresis (CE) with native fluorescence and laserβinduced fluorescence (LIF) detection are described herein. Using native fluorescence, normorphine, morphine, 6βacetyl morphine