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Direct demonstration of involvement of the adaptor protein ShcA in the regulation of Ca2+-induced platelet aggregation

✍ Scribed by Tomohito Higashi; Akira Yoshioka; Ryutaro Shirakawa; Arata Tabuchi; Hiroaki Nishioka; Toru Kita; Hisanori Horiuchi


Book ID
116289040
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
539 KB
Volume
322
Category
Article
ISSN
0006-291X

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The adaptor protein shc is involved in t
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The activation of protein tyrosine kinase(s) (PTK) is a critical event required for the development of NK cell-mediated cytotoxicity. Here we demonstrate that the adaptor protein shc undergoes tyrosine phosphorylation during the generation of antibody-dependent cellular cytotoxicity (ADCC) and natur