In a 'blind' trial on 50 male asymptomatic microfilaraemic subjects with Wuchereria bancrofti infection, the safety, tolerability and filaricidal efficacy of a single dose of albendazole (alb) 600 mg alone or in combination with ivermectin (iver) 400 micrograms/kg or diethylcarbamazine citrate (DEC)
Direct assessment of the adulticidal efficacy of a single dose of ivermectin in bancroftian filariasis
β Scribed by Gerusa Dreyer; Joaquim Noroes; Fernando Amaral; Adauto Nen; Zulma Medeiros; Amaury Coutinho; David Addiss
- Book ID
- 107850782
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 423 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0035-9203
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When ivermectin and diethylcarbamazine (DEC) are given simultaneously in a single dose to persons with Wkhereria bancrofi infection, the resulting suppression of microfilaraemia is more profound and sustained than when either drug is given alone. To assess whether this effect is a result of enhanced