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Direct Assessment of MHC Class I Binding by Seven Ly49 Inhibitory NK Cell Receptors

✍ Scribed by Thomas Hanke; Hisao Takizawa; Christopher W McMahon; Dirk H Busch; Eric G Pamer; Joseph D Miller; John D Altman; Yang Liu; Dragana Cado; Francois A Lemonnier; Pamela J Bjorkman; David H Raulet

Book ID
117722511
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
162 KB
Volume
11
Category
Article
ISSN
1074-7613

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## Abstract Murine natural killer (NK) cells are inhibited by target cell MHC class I molecules __via__ Ly49 receptors. However, Ly49 receptors can be made inaccessible to target cell MHC class I by a __cis__ interaction with its MHC class I ligand within the NK cell membrane. It has recently been