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Direct Alkynylation of Indole and Pyrrole Heterocycles

✍ Scribed by Jonathan P. Brand; Julie Charpentier; Jérôme Waser


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
324 KB
Volume
48
Category
Article
ISSN
0044-8249

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Single and Consecutive Cyclization React
✍ José Barluenga; Jaime García-Rodríguez; Ángel L. Suárez-Sobrino; Miguel Tomás 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 2 views

## Abstract The reactivity of alkynyl and enynyl Fischer carbene complexes towards 8‐azaheptafulvenes is examined. Alkynyl carbenes **1 a**–**f** undergo regioselective [8+2] heterocyclization with 8‐aryl‐8‐azaheptafulvenes **2 a**, **b** providing cycloheptapyrroles **3** and **4** with metal carb