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Direct aldol reactions catalyzed by 1,1,3,3-tetramethylguanidine lactate without solvent

โœ Scribed by Zhu, Anlian; Jiang, Tao; Wang, Dong; Han, Buxing; Liu, Li; Huang, Jun; Zhang, Jicheng; Sun, Donghai


Book ID
118264433
Publisher
Royal Society of Chemistry
Year
2005
Tongue
English
Weight
183 KB
Volume
7
Category
Article
ISSN
1463-9262

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## Abstract The asymmetric aldolโ€Tishchenko reaction of aromatic aldehydes with aliphatic and aromatic ketones has been developed as an efficient strategy for the synthesis of __anti__โ€1,3โ€diols in good yield with high diastereocontrol and good levels of enantioselectivity. This dominoโ€type reactio