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Direct action of BRL 38227 and glibenclamide on intracellular calcium stores in cultured airway smooth muscle of rabbit

โœ Scribed by Lorna C. Chopra; Charles H.C. Twort; Jeremy P.T. Ward


Book ID
117959703
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
348 KB
Volume
105
Category
Article
ISSN
0007-1188

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Relaxant Effects of the Potassium Channe
โœ D.R. Buckle; J.R.S. Arch; N.E. Bowring; K.A. Foster; J.F. Taylor; S.G. Taylor; D ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier ๐ŸŒ English โš– 525 KB

SUMMARY: The airways relaxant effects and mechanism of action of the potassium channel activators BRL 38227 and pinacidil have been compared in guinea-pig and human airways. BRL 38227 was a potent relaxant in guinea-pig isolated trachealis ( \(\mathrm{IC}_{50}=4.9 \times 10^{-7} \mathrm{M}\) against