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Direct access to the cooperative substructure of proteins and the protein ensemble via cold denaturation

✍ Scribed by Babu, Charles R; Hilser, Vincent J; Wand, A Joshua


Book ID
109966831
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
621 KB
Volume
11
Category
Article
ISSN
1545-9993

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## Abstract Characterizing the native ensemble of protein is an important yet difficult objective of structural biology. The structural dynamics of protein macromolecules play key roles in biological function, but the short lifetimes and low population of near‐native states of the protein ensemble