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Direct 19f NMR spectroscopic observation of 5-fluorouracil metabolism in the isolated perfused mouse liver model

โœ Scribed by S. Cabanac; M. C. Malet-Martino; M. Bon; R. Martino; J. F. Nedelec; J. L. Dimicoli

Book ID
102958846
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
775 KB
Volume
1
Category
Article
ISSN
0952-3480

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Fluorine-19 NMR spectroscopic studies of
Fluorine-19 NMR spectroscopic studies of the metabolism of 5-fluorouracil in the liver of patients undergoing chemotherapy
โœ Walter Wolf; Michael J. Albright; Michael S. Silver; Horst Weber; Ulrich Reichar ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 495 KB

Fluorine-19 nuclear magnetic resonance allows direct observation of fluorinated drugs and their metabolites in the human body without background signal from the tissue. A well-known fluorinated chemotherapeutic drug, 5-fluorouracil, and its metabolites were observed noninvasively in the liver of thr