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Dipolar 1,3-cycloaddition of arylnitriloxides on 1,2-dihydroisoquinolines in a two-phase medium

✍ Scribed by Said Kitane; Amina Taimi; Abdelmejid Bahloul; Abdelfatah Sebban; Mohamed Berrada; Jean-Pierre Joly

Publisher: Journal of Heterocyclic Chemistry
Year: 2000
Tongue: English
Weight: 228 KB
Volume: 37
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570370639

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✦ Synopsis

Abstract

The 1,3‐dipolar cycloaddition of arylnitriloxides on 1,2‐dihydroisoquinoline derivatives led to new 3‐aryl, 3a‐8,9,9a‐tetrahydro[5,4‐c]‐isoxazoloisoquinoline adducts. The regioselectivity of the cycloaddition reactions is discussed on the basis of ^1^H and ^13^C NMR data.

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