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Diphtheria toxin: Requirement for active protein synthesis for inactivation of aminoacyl transferase II in the intact mammalian cell

✍ Scribed by Mark E. Smulson; Cecile Rideau; Samuel Raeburn


Book ID
115744081
Publisher
Elsevier Science
Year
1970
Weight
235 KB
Volume
224
Category
Article
ISSN
0005-2787

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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) Ξ΄ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCΞ΄ has a negative effect on cell proliferation. However, the mode of PKCΞ΄ activation, the cell cycle stage requ