𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Diphenhydramine-selective plastic membrane sensor and its pharmaceutical applications

✍ Scribed by Arzum Erdem; Mehmet Ozsoz; Levent Kirilmaz; Emrah Kilinc; Tayfun Dalbasti

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
362 KB
Volume
9
Category
Article
ISSN
1040-0397

No coin nor oath required. For personal study only.

✦ Synopsis

Different types of PVC-matrix ion-selective electrodes (ISEs) that respond to the cationic form of diphenhydramine (Dph) are described. Three ionpairing agents, namely tetraphenylborate (TPB), phosphotungstate (PT), reineckate (RN) are investigated. The best PVC polymeric membrane contains Dph-TPB as active material. The electrode, based on the ion-pair complex with TPB anion shows near-Nemstian response in the concentration range lo-* to 3.5 x M (Dph.HCI). Changing pH within the range 2.0-7.5 did not affect the electrode performance. The standard electrode potentials were determined at different temperatures and used to calculate the isothermal coefficient of the electrode (0.001 56 VPC) The electrode showed a good selectivity for Dph with respect to a large number of inorganic and organic cations. The standard addition method and potentiometric titration were applied to determine Dph amounts in pharmaceutical preparations. The Dph selective membrane electrode was also applied to the determination of the dissolution profile of Dph tablets. The dissolution results were compared with spectrophotometrically determined ones.

πŸ“œ SIMILAR VOLUMES

Selective Transport Membranes and their
Selective Transport Membranes and their Applicability for Novel Sensors
✍ Werner E. Morf; Marin Huser; Bernhard Lindemann; Peter Schulthess; Wilhelm Simon πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 German βš– 505 KB

Selective transport of given substrates through artificial membranes can be achieved by incorporation of electrically neutral or charged carriers. Such mediated transport described for alkali and alkaline-earth metal cations is reported here for the first time for certain anions using cobyrinate-typ

Plasticized poly(vinyl chloride) as a pe
Plasticized poly(vinyl chloride) as a permselective barrier membrane for high-selectivity amperometric sensors and biosensors
✍ I.M. Christie; P.H. Treloar; P. Vadgama πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 711 KB

A poly(vmyl chloride) (PVC) membrane system is described for use as a high-selectmty barrier in amperometnc sensors and biosensors Membrane casting and electrode fabncation techniques are presented The membrane properties, both physical and with respect to permselectivity, are outlined This new form

Characterization of a Silver Modified PV
Characterization of a Silver Modified PVCAc Electrode and Its Application as a Ag(I)-Selective Potentiometric Sensor
✍ D. M. SejmanoviΔ‡; B. B. PetkoviΔ‡; M. V. Budimir; S. P. Sovilj; V. M. JovanoviΔ‡ πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 234 KB

## Abstract An all solid‐state Ag(I) ion‐selective electrode has been prepared by simply immersing a glassy carbon rod coated with PVCAc, which contained plasticizer and additive but no ionophore, into the AgNO~3~ solution. The response of the electrode was linear with a Nernstian slope of 60.25β€…mV