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Dipeptide-Catalyzed Direct Asymmetric Aldol Reaction in the Presence of Water.

✍ Scribed by Meng Lei; Lanxiang Shi; Gong Li; Shilv Chen; Weihai Fang; Zemei Ge; Tieming Cheng; Runtao Li


Publisher
John Wiley and Sons
Year
2007
Weight
47 KB
Volume
38
Category
Article
ISSN
0931-7597

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Direct Catalytic Asymmetric Aldol Reacti
✍ Joanna Paradowska; Maciej Stodulski; Jacek Mlynarski πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 94 KB πŸ‘ 2 views

## Abstract A combination of zinc triflate and chiral __C~2~__‐symmetrical prolinamide ligand leads to high enantioselectivities in direct aldol reactions essentially assisted by water. The presence of 5 mol % of the catalyst affords an asymmetric intermolecular aldol reaction between unmodified ke