Diode laser hair removal does not interfere with botulinum toxin A treatment against axillary hyperhidrosis
✍ Scribed by Anna Paul; Gottfried Kranz; Andreas Schindl; Georg S. Kranz; Eduard Auff; Thomas Sycha
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 84 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background and Objective
The possible interference of combined laser hair removal and Botulinum toxin A (BoNT/A) injections in the treatment of axillary hyperhidrosis has not previously been explored. In order to examine this potential interference, we assessed the effect of BoNT/A on axillary hyperhidrosis with and without concomitant diode laser axillary hair removal.
Study Design/Materials and Methods
In a prospective, double blind, randomized cross over trial, nine patients suffering from primary axillary hyperhidrosis were laser‐treated on one randomly assigned axilla. One week later, both axillas were injected intradermally with BoNT/A (100 MU per axilla). During the same session, the previously untreated axilla was lasered. Axillary sweat rates (in g/5 minutes.) were determined by gravimetry and compared at rest, during mental exercise, and during physical exercise. Additionally, subjective outcome measures were assessed by a visual analogue scale, Dermatology Life Quality Index, and Global Clinical Impression score.
Results
No differences were found regarding the effect of BoNT/A on previously laser‐treated and laser co‐treated sides over time course for any of the outcome parameters. Sweat production was reduced 3 weeks after BoNT/A treatment by 93.5% at rest, 96.5% during mental exercise, and 67% during physical exercise.
Conclusions
Concomitant laser hair removal does not interfere with BoNT/A treatment on axillary hyperhidrosis. Lasers Surg. Med. 42:211–214, 2010. © 2010 Wiley‐Liss, Inc.