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Dinucleotide (CA/GT) repeat polymorphism in intron 17B of the cystic fibrosis transmembrane conductance regulator (CFTR) gene

✍ Scribed by N. Morral; E. Girbau; J. Zielenski; V. Nunes; T. Casals; L. -C. Tsui; X. Estivill


Publisher
Springer
Year
1992
Tongue
English
Weight
107 KB
Volume
88
Category
Article
ISSN
0340-6717

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Cystic fibrosis, the most common lethal genetic disease in the white population, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Analysis of DNA from a pancreatic insufficient patient by chemical mismatch cleavage and subsequent DNA sequencing led to th