Dinuclear Zn-Catalyzed Asymmetric Alkynylation of Unsaturated Aldehydes.
β Scribed by Barry M. Trost; Andrew H. Weiss; Axel Jacobi van Wangelin
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 35 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The asymmetric alkynylation of aldehydes catalyzed by bifunctional Zn(salen) catalyst was realized. With a Kozlowski salen ligand (7e) bearing secondary basic 1βpiperidinylmethyl groups at Cβ3 and Cβ3β², the enhanced catalytic reactivity and stereoselectivity in comparison with that of n
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