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Diminished hypotensive response to isoproterenol in streptozotocin-diabetic rats

✍ Scribed by Jobidon, C.; Nadeau, A.; Tancrède, G.; Rousseau-Migneron, S.


Book ID
123384337
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
640 KB
Volume
20
Category
Article
ISSN
0306-3623

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Lack of cardiotoxic effect of isoprotere
✍ Ole Gøtzsche 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 925 KB

The well known cardiotoxic effect of isoproterenol (ISO) was investigated in normal and streptozotocin diabetic rats. Seven days after the subcutaneous injection of ISO (15 mg/kg) the hearts were perfusion fixed and 12 sections from each heart were stained (Masson's trichrome). ISO induced myocardia