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Diminished calcium influx in lectin-stimulated T cells from old mice

โœ Scribed by Richard A. Miller; Bruce Jacobson; Gary Weil; Elizabeth R. Simons

Book ID
102884004
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
624 KB
Volume
132
Category
Article
ISSN
0021-9541

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Defective control of cytoplasmic calcium
Defective control of cytoplasmic calcium concentration in T lymphocytes from old mice
โœ Richard A. Miller; Ben Philosophe; Irene Ginis; Gary Weil; Bruce Jacobson ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 928 KB

Cytoplasmic calcium concentration ([Ca],) rises within minutes of exposure of T lymphocytes to a mitogen. T cells from old mice are defective in this reaction, a defect that could reflect either altered signal transduction or instead a more general age-associated change in intracellular calcium regu