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Dimerization of the Extracellular Domain of the Erythropoietin (EPO) Receptor by EPO: One High-Affinity and One Low-Affinity Interaction

✍ Scribed by Philo, John S.; Aoki, Kenneth H.; Arakawa, Tsutomu; Narhi, Linda Owers; Wen, Jie


Book ID
127325258
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
553 KB
Volume
35
Category
Article
ISSN
0006-2960

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## Abstract The second extracellular loop (ECL2) of the Noc receptor has been proposed to be involved in ligand binding and selectivity. The interaction of Noc with a constrained cyclic synthetic peptide, mimicking the ECL2, has been studied using fluorescence and NMR spectroscopies. Selective bind