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Dihydroorotate Dehydrogenase Inhibitors: Quantitative Structure-activity Relationship Analysis

✍ Scribed by Shijun Ren; Sharon K. Wu; Eric J. Lien


Book ID
110308247
Publisher
Springer US
Year
1998
Tongue
English
Weight
652 KB
Volume
15
Category
Article
ISSN
0724-8741

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## Abstract Structure‐based quantitative structure‐activity relationship (QSAR) studies on a series of checkpoint kinase 1 (Chk1) inhibitors were performed to find the key structural features responsible for their inhibitory activity. Molecular docking was employed to explore the binding mode of al