Dihydrodipicolinate synthase of lysine excreting and non excreting strains of bacillus megaterium

✍ Scribed by M. Chatterjee; S. P. Chatterjee; A. K. Banerjee

• Book ID: 101403617
• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 198 KB
• Volume: 10
• Category: Article
• ISSN: 0138-4988
• DOI: 10.1002/abio.370100414

✦ Synopsis

Dihydrodipicolinate synthase activity of lysine producing strain of Bacillus megaterium and its high yielding mutant AECr 60r was highest during the end of the exponential phase and remained a t the same level during the stationary phase when major bulk of lysine was accumulated. In cornparision in a lysine non producing strain of B. megaterium the activity of the enzyme was low. Lysine producing strains has DHD synthase with two specialities, persistence during the stationary phase and insensitivity to repression by exogenous lysine. The high yielding mutant has increased DHD synthase activity which was not sensitive to feed back inhibition with lysine.