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Dihydro-1,4-pyrans. IV. The Synthesis of γ-Benzoyl-γ-butyrolactone and α-Hydroxy-δ-benzoylvaleric Acid

✍ Scribed by Fuson, Reynold C.; Davis, M. E.; Wojcik, B. H.; Turck, J. A. V.


Book ID
127273937
Publisher
American Chemical Society
Year
1934
Tongue
English
Weight
326 KB
Volume
56
Category
Article
ISSN
0002-7863

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Chemistry of ketene acetals IV. A simple
✍ R. W. Aben; R. Hofstraat; J. W. Scheeren 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 494 KB

## Abstract α‐Acyloxy aldehydes (**2a,b**) react with 1,1‐dimethoxypropene (**1**) in the presence of ZnCl~2~ to yield 2,2‐dimethoxy‐3‐methyloxetanes (**3a,b**). Stronger electron‐withdraxing acyl groups are necessary for the analogous conversion ofα‐acyloxy ketones (**2c,d,e**). Hydrolysis of the