The behaviour of nerve and muscle fibers can be simulated by computers using physiologically established equations. This paper discusses several local models and their applications. Spatial models are necessary for modelling propagating activities of fibers. Spatial models can be obtained by the co
Digital simulation of the membrane voltages and currents in nerve and muscle fibers
โ Scribed by E.W. Owen; W. Waring; F.F. Shoji; C.V. Prakash
- Publisher
- Elsevier Science
- Year
- 1976
- Weight
- 539 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0010-468X
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โฆ Synopsis
This paper describes digital computer simulations of the membrane voltages and currents in axons and muscle fibers. The simulations, which allow calculations ona nonuniform fiber, are based on the discrete Hodgkin-Huxley and Falk-Fatt equations. An efficient algorithm is used to solve the set of equations generated. Calculations are made of the voltage and current at the natural end of a muscle fiber and the results are compared with measurements by other investigators.
๐ SIMILAR VOLUMES
A study was made of synaptic currents in voltageclamped muscle fibers of the frog. Fast, submaxillaris, and slow muscle fibers are innervated by nerve fibers of different conduction velocities. To avoid spatial complications, transmitter release by nerve impulses was restricted to the site of record
The work dexrihed in this paper was done under a contract, recommeiideb by the Committee on Medical Research, between the O!Xce of Scientific Research and Development and the Cornell University Medical Collegr.