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Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice

โœ Scribed by Robert B. Chadwick; Liming Bu; Hongrun Yu; Yan Hu; Jon E. Wergedal; Subburaman Mohan; David J. Baylink

Book ID
109080432
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
330 KB
Volume
15
Category
Article
ISSN
1067-1927

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Early and delayed toxicity of a single dose of 300 mg kg-' cyclophosphamide (CP) was investigated in male DBAR and C57BL/6 mice. Early toxicity (up to 30 days after CP administration) resulted in 36.6% lethality in DBA12 and no mortality in C57BId6 mice. Delayed toxicity (after 30 days) occurred pr