Digestion and absorption of trioleoyl-thioglycerol in the rat

✍ Scribed by B. Åkesson; S. Gronowitz; P. Michelsen

• Book ID: 103042065
• Publisher: Elsevier Science
• Year: 1979
• Tongue: English
• Weight: 281 KB
• Volume: 23
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(79)90037-9

✦ Synopsis

A triacylglycerol analogue, rac-l,2-di-O-oleoyl-3-S-oleoyl-3-thioglycerol, was fed to rats and chyle acylglycerols were analyzed. Triacylglycerol was the dominating chyle lipid but X-triacyl-1-thioglycerol constituted approx. 6% of total chyle lipids. Its identity was verified by ultraviolet and mass spectra and its stereochemical structure by ORD and CD. The proportions of triacyl-l-thio-sn-glycerol/triacyl-3-thio-sn-glycerol were 63•37 and 78[22 in two experiments. Possible reasons for this stereospecificity are discussed. The study shows that the stereoehemieal configuration of lipids isolated from biological material can be assessed by ORD and CD.