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Difluoromethylornithine-induced amplification of ornithine decarboxylase genes in Ehrlich ascites carcinoma cells

✍ Scribed by L. Alhonen-Hongisto; A. Kallio; R. Sinervirta; P/ Seppänen; K.K. Kontula; O.A. Jänne; J. Jänne


Book ID
115758326
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
664 KB
Volume
126
Category
Article
ISSN
0006-291X

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D,L-α-DIFLUOROMETHYLORNITHINE, AN IRREVE
✍ Shailesh Kumar Choudhary; Dipali Sharma; Aparna Dixit 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 171 KB

In the present study, the effect of D,L-alpha-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), on Friend's murine erythroleukemia (MEL) cell differentiation is investigated. DFMO was able to induce differentiation of MEL cells in culture as determined by ha