Convenient method for the preparation of
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Atsushi Ogawa; Kazunari Sakagami; Akiko Shima; Hitoshi Suzuki; Satsuki Komiya; Y
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Article
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2002
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Elsevier Science
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French
โ 75 KB
Hydroxy-1-phenylthio-2-alkynes (5) reacted with dihydropyran to afford the corresponding 4-tetrahydropyranyloxy derivatives which, on treatment with KHMDS, gave a mixture of (E)-and (Z)-1-phenylthio-3-alken-1-ynes, with the former predominant. When MeLi was used in the place of KHMDS, the (Z)-isomer