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Difluoromethionine as a Novel 19 F NMR Structural Probe for Internal Amino Acid Packing in Proteins

✍ Scribed by Cleve, Paul; Robinson, Valerie; Duewel, Henry S.; Honek, John F.


Book ID
127149413
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
74 KB
Volume
121
Category
Article
ISSN
0002-7863

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## Abstract The conformation, alignment and dynamic behavior of membrane‐bound peptides is readily accessible by solid‐state ^19^F‐NMR spectroscopy, but it has been difficult to incorporate suitable ^19^F‐labelled amino acids into synthetic peptides. To avoid the drawbacks of previously used labels