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Diffusion-weighted images of the liver: Comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide

✍ Scribed by Shinji Naganawa; Chiho Sato; Tatsuya Nakamura; Hisashi Kumada; Takeo Ishigaki; Shunichi Miura; Katsuya Maruyama; Osamu Takizawa

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
338 KB
Volume
21
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Purpose

To study the recognition of malignant lesions of the liver on diffusion‐weighted images (DWI) can be improved by the administration of superparamagnetic iron oxide (SPIO).

Materials and Methods

Pre‐ and post‐SPIO mediated DWI of the liver was compared in six patients with suspected malignant liver lesions at 1.5 Tesla using a parallel imaging technique.

Results

Post‐SPIO DWI showed improved contrast‐to‐noise ratio between malignant lesions and liver. Furthermore, the spleen signal was decreased on post‐SPIO DWI, thus avoiding the overlap of the spleen and left lobe of the liver on maximum intensity projections (MIP).

Conclusion

Recognition of malignant lesions of the liver was improved by SPIO on DWI. On MIP images of DWI, SPIO helped to decrease the overlap of spleen signal on the liver in some projection angles. J. Magn. Reson. Imaging 2005;21:836–840. © 2005 Wiley‐Liss, Inc.

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