𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Diffusion tensor imaging in a rat model of Parkinson's disease after lesioning of the nigrostriatal tract

✍ Scribed by Nadja Van Camp; Ines Blockx; Marleen Verhoye; Cindy Casteels; Frea Coun; Alexander Leemans; Jan Sijbers; Veerle Baekelandt; Koen Van Laere; Annemie Van der Linden

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
380 KB
Volume
22
Category
Article
ISSN
0952-3480

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Regional alterations of brain microstruc
Regional alterations of brain microstructure in Parkinson's disease using diffusion tensor imaging
✍ Wang Zhan; Gail A. Kang; Graham A. Glass; Yu Zhang; Cheryl Shirley; Rachel Milli 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 467 KB 👁 1 views

## Abstract This study tested the hypothesis that diffusion tensor imaging can detect alteration in microscopic integrity of white matter and basal ganglia regions known to be involved in Parkinson's disease (PD) pathology. It was also hypothesized that there is an association between diffusion abn

Urinary 8-OHdG elevations in a partial l
Urinary 8-OHdG elevations in a partial lesion rat model of parkinson's disease correlate with behavioral symptoms and nigrostriatal dopaminergic depletion
✍ Yoichiro Kikuchi; Takao Yasuhara; Takashi Agari; Akihiko Kondo; Satoshi Kuramoto 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB

## Abstract Increased oxidative stress contributes to pathogenesis of Parkinson's disease (PD). 8‐hydroxy‐2'‐deoxyguanosine (8‐OHdG) is the oxidation product most frequently measured as an indicator of oxidative DNA damage. Several studies have shown increased 8‐OHdG in PD patients. There are few b

Nonmotor symptoms in Parkinson's disease
Nonmotor symptoms in Parkinson's disease: Investigating early-phase onset of behavioral dysfunction in the 6-hydroxydopamine-lesioned rat model
✍ Igor Branchi; Ivana D'Andrea; Monica Armida; Tommaso Cassano; Antonella Pèzzola; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 320 KB 👁 1 views

## Abstract To investigate the psychiatric symptoms accompanying the early phases of Parkinson's disease (PD), we injected adult rats with 10.5 μg 6‐hydroxydopamine (6‐OHDA) bilaterally into the dorsal striatum. The resulting neurodegeneration led, 12 weeks after injection, to a mild (36%) reductio

Altered extracellular striatal in vivo b
Altered extracellular striatal in vivo biotransformation of the opioid neuropeptide dynorphin A(1–17) in the unilateral 6-OHDA rat model of Parkinson's disease
✍ Rebecka Klintenberg; Per E. Andrén 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB

## Abstract The __in vivo__ biotransformation of dynorphin A(1–17) (Dyn A) was studied in the striatum of hemiparkinsonian rats by using microdialysis in combination with nanoflow reversed‐phase liquid chromatography/electrospray time‐of‐flight mass spectrometry. The microdialysis probes were impla