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Diffusion- and perfusion-weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)

✍ Scribed by Johannes Bernarding; Jürgen Braun; Hans-Christian Koennecke

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 557 KB
Volume: 15
Category: Article
ISSN: 1053-1807
DOI: 10.1002/jmri.10045

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✦ Synopsis

Abstract

To monitor changes of brain tissue metabolism in acute demyelinating encephalitis (ADEM), we examined a patient with suspected ADEM by serial MRI including diffusion‐ and perfusion‐weighted imaging (DWI, PWI). Within the inflammatory tissue, the apparent diffusion coefficients were reduced, normal, and increased. Perfusion varied between reduced and normal values, except for small hyperperfused regions. Combining standard MRI with DWI and PWI may elucidate different overlapping phases in cerebral inflammation. J. Magn. Reson. Imaging 2002;15:96–100. © 2002 Wiley‐Liss, Inc.

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