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Diffuse lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: A case report

✍ Scribed by V. M. S. de Bruin; A. J. Lees; S. E. Daniel


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
916 KB
Volume
7
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

A 67‐year‐old man with a family history of parkinsonism had visual complaints due to difficulty in convergence, which was followed 2 years later by development of bradykinesia and rigidity. The diagnosis of Steele Richardson‐Olszewski syndrome was made on the basis of a supranuclear gaze palsy, bradykinesia, rigidity, and poor response to levodopa. However, subsequent neuropathological examination revealed diffuse Lewy body disease with no evidence of neurofibrillary tangles involving either subcortical or brain stem structures.