✍ Scribed by Carsten Zornig; Gerd Thoma; Sören Schröder
No coin nor oath required. For personal study only.
Smooth muscle cell tumors of the large bowel excluding the rectum are extremely rare. The case of a 30year-old patient, who had ulcerative colitis for 5 years, is reported. Because of uncontrollable bleeding a proctocolectomy was performed. Along the whole colon the authors found more than 50 polypous tumors with a diameter up to 5 cm. Histologically all of these tumors were classified as leiomyosarcomas. The authors believe this to be the first reported case of multicentric leiomyosarcoma of the colon and of such a tumor associated with a history of ulcerative colitis.
Cancer 65570472. 1990.
RIMARY MALIGNANT mesenchymal tumors of the P gastrointestinal tract are rare. Predominantly it is a matter of leiomyosarcomas and malignant non-Hodgkin's lymphomas. Leiomyosarcomas are mostly found in the stomach (6 1 %), 24% in the small bowel, 7% in the rectum, and in only 3% in the Until 1979, 43 cases of leiomyosarcomas in the large bowel were r e p ~r t e d . ~ There has never been a report about a multicentric leiomyosarcoma in the literature. An additional characteristic of this case is the long-lasting history of ulcerative colitis. This is the reason for us to report this case.
A 30-year-old man was transferred to our clinic because of acute gastrointestinal bleeding. For 5 years he had had ulcerative colitis with typical, and in the course of time, increasing symptoms. Recurrent episodes of the colitis necessitated yearly hospitalizations in another clinic. During the last 2 years he had to be treated by high doses of cortisone and azathioprin. Twice he was resuscitated because of toxic pulmonary edema. Multiple colonoscopies, the last one 4 months before, showed each time typical findings of ulcerative colitis without evidence of tumor growth.
Bleeding could be controlled conservatively. After the general condition of the patient had improved, another colonoscopy was performed. Now single pseudopolyps were found in the rectum. At a height of 10 cm, there were some large polypous tumors with slight bleeding at contact. Orally they increased in number.
📜 SIMILAR VOLUMES
have already been in situ for 2 years, and have in that time given rise to no complications.