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Difficult Diagnoses in Breast Pathology

โœ Scribed by Juan P. Palazzo MD


Publisher
Demos Medical Publishing
Year
2011
Tongue
English
Leaves
259
Edition
1
Category
Library

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โœฆ Synopsis


Breast cancer is the second leading cause of cancer death in women in the United States. For the pathologist, almost any breast lesion may produce diagnostic difficulty, especially due to frequently small samples (core biopsy specimens) and a variety of mimics and variants seen in specific types of lesions. Additionally, the difficulty of breast lesion diagnosis has risen dramatically in recent years due to the increased emphasis on stratifying patients for appropriate therapy on an individual basis; the wider range of both local and systemic therapeutic options, and the potential for earlier diagnosis through increased mammographic breast screening leading to a higher likelihood of a favorable outcome.

Difficult Diagnoses in Breast Pathology provides a highly visual presentation of the major problems and questions that a pathologist is likely to encounter in the evaluation of common and uncommon breast diseases. Coverage includes needle core biopsy interpretation, diagnosis of precursor lesions, early stage disease, and recognition of neoplastic mimics and other misleading variants. In addition, this book emphasizes particularly difficult areas including the use of newer immunohistochemical markers. Throughout, the emphasis is on an easily accessible presentation with tables and lists of key points summarizing major findings and numerous high-quality images supporting the text. Difficult Diagnoses in Breast Pathology will be a valuable reference for every pathologist who deals with the diagnosis of breast diseases.

Difficult Diagnoses in Breast Pathology Features:

  • Each chapter authored by recognized expert in the area
  • Hundreds of high-quality images
  • Tables and key points in each chapter summarize the most important findings
  • Coverage based on addressing in detail the real-world diagnostic problems the pathologist will face in daily practice

โœฆ Table of Contents


Index......Page 1
Half Title......Page 2
Title......Page 4
Copyright......Page 5
Contents......Page 6
Preface......Page 8
Contributors......Page 10
Difficult Diagnoses in Breast Pathology......Page 12
The Diagnostic Challenges of Core Needle Biopsy Interpretation......Page 13
Atypical Ductal hyperplasia......Page 14
Papillary lesions......Page 17
Lobular lesions......Page 21
Fibroepithelial lesions......Page 24
Radial scar......Page 26
Mucinous lesions......Page 30
References......Page 31
Morphologic Precursors of Mammary Carcinoma and Their Mimics......Page 35
ATYPICAL DUCTAL HYPERPLASIA......Page 36
DUCTAL CARCINOMA IN SITU......Page 40
Ductal Carcinoma In Situ With Unusual Morphology......Page 44
LOBULAR NEOPLASIA......Page 54
References......Page 63
Papillary Lesions of the Breast......Page 67
Benign Papillary Lesions of the Breast......Page 68
Malignancies Involving Papillary Lesions......Page 80
Malignant Papillary Lesions of the Breast......Page 82
Key points......Page 93
References......Page 94
Flat Epithelial Atypia......Page 99
PATHOLOGIC FEATURES......Page 100
BIOLOGIC SIGNIFICANCE......Page 107
DIFFERENTIAL DIAGNOSIS......Page 111
MANAGEMENT......Page 118
TERMINOLOGY......Page 121
CONCLUSION......Page 122
REFERENCES......Page 123
Adenosis: Mimickers of Carcinoma......Page 125
SCLEROSING ADENOSIS......Page 126
MICROGLANDULAR ADENOSIS......Page 132
ATYPICAL ADENOSIS AND CANCERIZATION OF ADENOSIS......Page 133
KEY POINTS......Page 136
REFERENCES......Page 137
Microinvasive Carcinoma: Diagnosis and Pitfalls......Page 139
PATHOLOGIC FEATURES......Page 140
MANAGEMENT......Page 154
KEY POINTS......Page 155
References......Page 156
Carcinomas With Good Prognosis......Page 157
PURE TUBULAR CARCINOMA......Page 158
INVASIVE CRIBRIFORM CARCINOMA......Page 161
PURE INVASIVE LOBULAR CARCINOMA......Page 162
PURE MEDULLARY CARCINOMA......Page 166
PURE MUCINOUS CARCINOMA......Page 168
ADENOID CYSTIC CARCINOMA......Page 170
LOW-GRADE SPINDLE CELL METAPLASTIC CARCINOMA......Page 173
LOW-GRADE ADENOSQUAMOUS CARCINOMA......Page 175
SECRETORY CARCINOMA......Page 176
REFERENCES......Page 177
Mesenchymal Lesions of the Breast......Page 183
Benign nonneoplastic stromal lesions......Page 184
Benign neoplastic stromal lesions......Page 186
MASS-FORMING CHRONIC FIBROINFLAMMATORY PROLIFERATIONS IN THE BREAST......Page 190
Fibroepithelial Lesions of the Breast......Page 192
Vascular lesions......Page 199
Key Points......Page 203
REFERENCES......Page 204
Lymphomas of the Breast......Page 207
PRIMARY LYMPHOMAS OF THE BREAST......Page 208
CONCLUSIONS......Page 220
REFERENCES......Page 221
Immunohistochemistry in Breast Pathology......Page 223
DIAGNOSTIC MARKERS......Page 224
MINIMAL DATA SET......Page 236
MARKERS BEYOND MINIMAL DATA SET......Page 240
MOLECULAR SUBTYPING......Page 242
REFERENCES......Page 248


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