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Differing effects of the inhibition of poly(ADP-ribose) polymerase on the course of oxidative cell injury in hepatocytes and fibroblasts

✍ Scribed by Kazuhiko Yamamoto; Kazuo Tsukidate; Farber L. John

Book ID
115783513
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
874 KB
Volume
46
Category
Article
ISSN
0006-2952

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Poly(ADP-ribose) polymerase (PARP) is a DNA-bind-induced apoptosis. After VP16 treatment with PARP ing protein involved in cellular response to various inhibition, a reduction in the depletion of the prolifgenotoxic agents. To understand the role of PARP erative compartment and a G2/M phase arrest a