Differing Effects of Rapamycin or Calcineurin Inhibitor on T-Regulatory Cells in Pediatric Liver and Kidney Transplant Recipients
β Scribed by T. Akimova; B. M. Kamath; J. W. Goebel; K. E. C. Meyers; E. B. Rand; A. Hawkins; M. H. Levine; J. C. Bucuvalas; W. W. Hancock
- Book ID
- 117963628
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 1015 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1600-6135
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## Background: Regulatory T-cells (Treg) are natural suppressors of autoimmunity. Previous studies indicate that immunosuppressive drugs, especially calcineurin-inhibitors, may interfere with Treg homeostasis. Inflammatory bowel disease (IBD) can relapse or develop de novo after liver transplantati
The severity of recurrent hepatitis C virus (HCV) is likely related to several factors. Controversial results have been reported regarding the effect of specific calcineurin-inhibitors. The aim of this research was to determine whether there are differences on posttransplantation outcome in HCV-infe